🌿 Bioidentical Hormone Replacement Therapy (BHRT): Whole-Body Benefits for Women in Perimenopause and Menopause
As you approach or go through menopause, your body makes less estrogen, progesterone, and sometimes testosterone. These changes can affect your entire body — not just your periods. Bioidentical hormone replacement therapy (BHRT) uses hormones that are chemically identical to what your body makes naturally to help relieve symptoms and protect long-term health.
Here’s how BHRT may benefit you — from head to toe.
🧠 Brain & Mood
Improves focus and memory
Helps stabilize mood and reduce anxiety or depression
May lower the risk of memory loss when started early in menopause
Backed by: The KEEPS Trial (2015) showed better mood and memory with transdermal estradiol and natural progesterone.
❤️ Heart & Blood Vessels
Supports healthy cholesterol levels
Keeps blood vessels more flexible and helps maintain blood flow
May reduce risk of heart disease when started near the time of menopause
Backed by: The ELITE Study (2016) found estrogen slowed artery thickening in women who started therapy early after menopause.
🦴 Bones & Joints
Helps prevent bone loss and osteoporosis
Reduces risk of fractures
May ease joint pain and stiffness
Backed by: The Women’s Health Initiative (WHI) showed hormone therapy reduced hip fractures by 33%.
🧬 Metabolism & Weight
Improves insulin sensitivity (helpful for prediabetes)
May help reduce belly fat
Helps maintain lean muscle mass
Backed by: KEEPS metabolic studies found improvements in blood sugar control and fat distribution.
🌸 Vaginal & Sexual Health
Reduces vaginal dryness, burning, and pain
Supports better sexual desire and comfort
May prevent frequent urinary tract infections (UTIs)
Backed by: North American Menopause Society guidelines and studies on testosterone and vaginal estrogen therapy.
🧴 Skin & Hair
Improves skin moisture, thickness, and elasticity
May reduce wrinkles and signs of aging
Helps slow hair thinning
Backed by: Research shows estrogen therapy supports skin collagen and improves skin structure.
😴 Sleep & Energy
Promotes deeper, more restful sleep
Reduces night sweats and hot flashes
Leads to more daytime energy
Backed by: Studies show that progesterone improves sleep quality and estrogen reduces disruptive night symptoms.
🛡️ Immune System & Inflammation
Lowers inflammation in the body
May reduce flares of autoimmune conditions in some women
Backed by: Estrogen shown to reduce levels of inflammatory markers like CRP and IL-6.
Is BHRT Safe?
When used properly, and under medical supervision, BHRT is considered safe and effective for many women. The safest forms are:
Transdermal estradiol (patch, cream, or gel)
Micronized progesterone (oral or vaginal)
Low-dose testosterone (for select women with low libido)
Is BHRT Right for You?
You may be a good candidate if you're experiencing:
Hot flashes, poor sleep, or mood swings
Vaginal dryness or painful sex
Low energy or reduced muscle mass, weight gain
Memory issues or brain fog
Loss of bone density
Your provider will consider your medical history and symptoms to personalize the best plan for you.
🩺 Talk to us today
BHRT is not one-size-fits-all. At Conowingo Wellness, we help you find the right dose, delivery method, and balance of hormones to support your health and well-being.
Dr. Rachel Rubin, board-certified urologist and sexual medicine expert, joins Peter Attia to dive deep into women’s sexual health, menopause, and hormone balance